Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903051 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL23027271 | 0.87 | NOTUM (0.45) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL14315405 | 0.85 | KDM4E (0.49) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL18880167 | 0.84 | LMNA (0.41) | SMN1; SMN2KDM4EHTTTP53MAPT | |
| SCHEMBL15606230 | 0.82 | HSD17B3 (0.47) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL23961976 | 0.79 | LMNA (0.38) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL16204548 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL23961901 | 0.79 | KDM4E (0.36) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL23962003 | 0.79 | LMNA (0.39) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL24701748 | 0.79 | KDM4E (0.37) | SMN1; SMN2KDM4EHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019242691-A1 | PACLITAXEL-LIPID-POLYSACCHARIDE DUAL-TYPE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 圣多利康制药责任有限公司 | 2019-12-26 | — | — | WO | disclosed |