Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 12/20 | 0.36 |
| ▸ | TDO2 | P48775 | 12/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15606230 | 0.89 | HSD17B3 (0.47) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL25891385 | 0.89 | TDO2 (0.35) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL24871031 | 0.88 | HSD17B3 (0.37) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL23962003 | 0.87 | LMNA (0.39) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL14315405 | 0.87 | KDM4E (0.49) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL20758286 | 0.85 | ALDH1A1 (0.39) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL23027271 | 0.84 | NOTUM (0.45) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL20805967 | 0.83 | MAPT (0.37) | KDM4EHTTSMN1; SMN2IDO1TDO2 | |
| SCHEMBL23961976 | 0.83 | LMNA (0.38) | KDM4EHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19604395 | 0.83 | HSD17B3 (0.35) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387628-A1 | MESSENGER RNA COMPRISING FUNCTIONAL RNA ELEMENTS AND USES THEREOF | MODERNATX, INC. | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387628-A1 | MESSENGER RNA COMPRISING FUNCTIONAL RNA ELEMENTS AND USES THEREOF | NSUN3, RNMT, NSUN2 | KDM4E 2467/4885HTT 2404/4885SMN1; SMN2 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.