Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189990 | 0.90 | RORC (0.40) | RORC | |
| SCHEMBL23504346 | 0.89 | RORC (0.39) | RORC | |
| SCHEMBL21605650 | 0.83 | NPBWR1 (0.38) | RORC | |
| SCHEMBL21606001 | 0.82 | RORC (0.44) | RORC | |
| SCHEMBL21598374 | 0.80 | RORC (0.45) | RORC | |
| SCHEMBL21605711 | 0.79 | RORC (0.39) | RORC | |
| SCHEMBL23478222 | 0.79 | PDE4A (0.38) | RORC | |
| SCHEMBL21605717 | 0.79 | RORC (0.39) | RORC | |
| SCHEMBL21605579 | 0.78 | RORC (0.49) | RORC | |
| SCHEMBL21607868 | 0.78 | RORC (0.48) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244001-A1 | 6-AMINOPYRIDIN-3-YL PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |