Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606323 | 0.89 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL21606274 | 0.83 | STING1 (0.51) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL24296024 | 0.82 | STING1 (0.49) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL18864289 | 0.81 | MAPT (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL21606273 | 0.81 | PARK7 (0.52) | MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL22000896 | 0.78 | STING1 (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL31065609 | 0.78 | STING1 (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL21932216 | 0.78 | STING1 (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL21932350 | 0.78 | STING1 (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A | |
| SCHEMBL31065616 | 0.78 | STING1 (0.73) | MAPTSMN1; SMN2TP53STING1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243823-A1 | AZAHETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |