Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606311 | 0.88 | GSK3B (0.49) | KMT2AMEN1MAPTALDH1A1HDAC6 | |
| SCHEMBL25414134 | 0.84 | POLB (0.49) | PARK7ALDH1A1HDAC6HSD17B10POLB | |
| SCHEMBL21606290 | 0.81 | MAPT (0.51) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21606280 | 0.79 | KMT2A (0.53) | PARK7KMT2AMEN1HPGDMAPT | |
| SCHEMBL23769015 | 0.79 | KMT2A (0.50) | PARK7KMT2AMEN1HPGDMAPT | |
| SCHEMBL23768997 | 0.78 | CASP1 (0.59) | KMT2AHPGDMAPTALDH1A1HTT | |
| SCHEMBL23768992 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL29978848 | 0.77 | ALDH1A1 (0.71) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL1201084 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1HPGDMAPTALDH1A1 | |
| SCHEMBL10938820 | 0.75 | HDAC6 (0.72) | KMT2AMEN1MAPTALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243823-A1 | AZAHETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |