Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214443 | 1.00 | BACE1 (0.51) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL3201279 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL8573735 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL8503544 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL3201276 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL7141149 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL8856846 | 0.84 | BACE1 (0.52) | BACE1SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL7939268 | 0.84 | TSHR (0.55) | SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9420155 | 0.84 | TSHR (0.55) | SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL3096445 | 0.82 | POLB (0.50) | SMN1; SMN2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243576-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | GUBRA APS (DK) | 2019-12-26 | — | — | WO | disclosed |