Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608031 | 1.00 | KCNK3 (0.37) | KCNK3NR1H2NR1H3GABRA1GABRG2 | |
| SCHEMBL21608569 | 0.88 | TRPV6 (0.37) | — | |
| SCHEMBL21608560 | 0.88 | TRPV6 (0.37) | — | |
| SCHEMBL21608552 | 0.88 | TRPV6 (0.37) | — | |
| SCHEMBL21608568 | 0.88 | TRPV6 (0.37) | — | |
| SCHEMBL23868330 | 0.88 | PTGDR2 (0.32) | HRH3 | |
| SCHEMBL23868331 | 0.88 | PTGDR2 (0.32) | HRH3 | |
| SCHEMBL23868333 | 0.88 | PTGDR2 (0.32) | HRH3 | |
| SCHEMBL21608183 | 0.86 | MGLL (0.35) | KCNK3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL21608177 | 0.86 | MGLL (0.35) | KCNK3GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |