Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21608081 | 1.00 | ATR (0.34) | ATRHCRTR1HCRTR2LOXLOXL2 | |
| SCHEMBL21608004 | 0.94 | LOX (0.37) | LOXLOXL2OGAEEDHTR1A | |
| SCHEMBL21608003 | 0.94 | LOX (0.37) | LOXLOXL2OGAEEDHTR1A | |
| SCHEMBL21608533 | 0.91 | KCNA5 (0.33) | LOXLOXL2OGAEEDKIT | |
| SCHEMBL21608534 | 0.91 | KCNA5 (0.33) | LOXLOXL2OGAEEDKIT | |
| SCHEMBL21608183 | 0.85 | MGLL (0.35) | LOXLOXL2OGAMGLL | |
| SCHEMBL21608177 | 0.85 | MGLL (0.35) | LOXLOXL2OGAMGLL | |
| SCHEMBL21608201 | 0.82 | KDM4E (0.34) | OGAEEDHTR1ASLC6A4TSHR | |
| SCHEMBL21608202 | 0.82 | KDM4E (0.34) | OGAEEDHTR1ASLC6A4TSHR | |
| SCHEMBL21608569 | 0.81 | TRPV6 (0.37) | OGAKCNH2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |