Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21607832 | 0.85 | L3MBTL1 (0.43) | L3MBTL1PTK2PIK3C3KDM4EHSP90AA1 | |
| SCHEMBL22574129 | 0.77 | PTK2 (0.51) | L3MBTL1PTK2PIK3C3KDM4EHSP90AA1 | |
| SCHEMBL19736366 | 0.75 | PIK3C3 (0.53) | L3MBTL1PTK2PIK3C3KDM4EHSP90AA1 | |
| SCHEMBL28270171 | 0.73 | L3MBTL1 (0.50) | L3MBTL1PIK3C3 | |
| SCHEMBL23015784 | 0.71 | L3MBTL1 (0.43) | L3MBTL1PTK2PIK3C3KDM4EHSP90AA1 | |
| SCHEMBL31006927 | 0.71 | ADORA3 (0.48) | L3MBTL1KDM4EADORA3CYP1A2ADORA1 | |
| SCHEMBL25298526 | 0.71 | ADORA3 (0.48) | L3MBTL1KDM4EADORA3CYP1A2ADORA1 | |
| SCHEMBL3660964 | 0.71 | PTK2 (0.57) | L3MBTL1PTK2KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL18900235 | 0.70 | L3MBTL1 (0.42) | L3MBTL1PTK2PIK3C3KDM4EHSP90AA1 | |
| SCHEMBL22207799 | 0.69 | UNG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | US | disclosed |
| WO-2019243531-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300900-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | L3MBTL1 1044/4885PTK2 3463/4885PIK3C3 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.