SCHEMBL21608342

SCHEMBL21608342

CSOCCn1ccc2c(Cl)nccc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.33
MAPT P10636 1/20 0.31
MCL1 Q07820 1/20 0.31
KLKB1 P03952 1/20 0.30
KLK1 P06870 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21608263 0.84 DYRK1A (0.39) RXFP1MAPTMCL1DYRK1A
SCHEMBL21608341 0.78 RXFP1 (0.34) RXFP1MAPTMCL1DYRK1A
SCHEMBL21608291 0.78 MCL1 (0.34) MAPTMCL1KLKB1KLK1
SCHEMBL21608320 0.77 DUT (0.41) RXFP1
SCHEMBL21603424 0.77 LMNA (0.48) RXFP1MAPTKLKB1KLK1
SCHEMBL21608318 0.76 RXFP1 (0.34) RXFP1MAPTKLKB1KLK1
SCHEMBL21608523 0.76 RXFP1 (0.36) RXFP1MAPTKLKB1KLK1
SCHEMBL21608521 0.75 GRIN2B (0.38) RXFP1
SCHEMBL21608306 0.74 HTR2A (0.33) RXFP1MAPTKLKB1KLK1
SCHEMBL21608284 0.74 KLKB1 (0.37) RXFP1MAPTMCL1KLKB1KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019243535-A1 OGA INHIBITOR COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO disclosed