SCHEMBL21608463

SCHEMBL21608463

CCCC(C)n1ccc2c(Cl)nccc21

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.48
BRD4 O60885 1/20 0.38
SLC6A2 P23975 1/20 0.33
RXFP1 Q9HBX9 1/20 0.31
ADA P00813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23791876 0.79 SLC2A1 (0.41) SLC2A1BRD4
SCHEMBL23791868 0.79 SLC2A1 (0.41) SLC2A1BRD4
SCHEMBL23791873 0.79 SLC2A1 (0.41) SLC2A1BRD4
SCHEMBL23791678 0.76 PGR (0.38)
SCHEMBL21608391 0.74 SLC2A1 (0.38) SLC2A1BRD4
SCHEMBL21603477 0.74 FPR2 (0.43)
SCHEMBL31560788 0.73 USP5 (0.40) RXFP1
SCHEMBL21608578 0.73 SLC2A1 (0.41) SLC2A1BRD4SLC6A2
SCHEMBL21608521 0.72 GRIN2B (0.38) RXFP1
SCHEMBL25810956 0.72 SLC2A1 (0.46) SLC2A1BRD4ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210277003-A1 OGA INHIBITOR COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2021-09-09 US disclosed
WO-2019243535-A1 OGA INHIBITOR COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210277003-A1 OGA INHIBITOR COMPOUNDS OGA, OGT, GRN SLC2A1 861/4885BRD4 2664/4885SLC6A2 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.