Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176369 | 0.79 | — | — | |
| SCHEMBL16982953 | 0.77 | FLT1 (0.35) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL13017260 | 0.76 | HTT (0.45) | MEN1KMT2ANPC1RAB9ACYP3A4 | |
| SCHEMBL14944914 | 0.75 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL16078374 | 0.75 | FLT1 (0.44) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL18495016 | 0.75 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL17327862 | 0.73 | KMT2A (0.41) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18516692 | 0.73 | MAOA (0.38) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4574528 | 0.71 | FLT1 (0.51) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL30628195 | 0.71 | FLT1 (0.51) | FLT1FLT4KDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243303-A1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2019-12-26 | — | — | WO | disclosed |