SCHEMBL21609072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17030757	0.82	KDR (0.50)	KDRFLT3KITAURKBMET
	SCHEMBL20963390	0.79	KDR (0.47)	KDRFLT3KITAURKBMET
	SCHEMBL15907820	0.79	KDR (0.47)	KDRFLT3KITAURKBMET
	SCHEMBL1781743	0.76	KDR (0.54)	KDRFLT3KITAURKBMET
	SCHEMBL3086613	0.75	KIT (0.34)	KDRFLT3KITMETEPHX2
	SCHEMBL2445430	0.75	KDR (0.58)	KDRFLT3KITAURKBMET
	SCHEMBL21660404	0.75	EPHX2 (0.49)	KDRFLT3KITEPHX2
	SCHEMBL5049132	0.74	KDR (0.43)	KDRFLT3KITAURKBMET
	Hydrochloric Acid SCHEMBL5103456	0.73	KDR (0.56)	KDRFLT3KITAURKBMET
	SCHEMBL6990623	0.72	FAAH (0.36)	KDRFLT3KITEPHX2HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.