SCHEMBL21609073

SCHEMBL21609073

COc1cccc(OC)c1[S+]([O-])Nc1noc2cc(Br)cc(OC)c12

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 19/20 0.40
KAT7 O95251 18/20 0.40
KAT6B Q8WYB5 10/20 0.40
KAT5 Q92993 7/20 0.40
KAT8 Q9H7Z6 7/20 0.40
KCNA5 P22460 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609189 0.82 KAT6A (0.41) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609265 0.79 ERN1 (0.38) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25564467 0.78 KAT6A (0.42) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817445 0.77 KAT6A (0.41) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817409 0.77 KAT6A (0.67) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817319 0.76 KAT7 (0.68) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817376 0.76 KAT7 (0.68) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817457 0.76 KAT6A (0.68) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26804388 0.76 KAT7 (0.68) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609055 0.75 KAT6A (0.66) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed