Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 17/20 | 0.42 |
| ▸ | KAT7 | O95251 | 16/20 | 0.42 |
| ▸ | KAT6B | Q8WYB5 | 8/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 5/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566914 | 0.80 | KAT6A (0.35) | KAT6AKAT7KAT6BSGMS2SGMS1 | |
| SCHEMBL22817409 | 0.80 | KAT6A (0.67) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL25561707 | 0.80 | KAT6A (0.67) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL30360820 | 0.80 | KAT6A (0.67) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL22817457 | 0.78 | KAT6A (0.68) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609073 | 0.78 | KAT6A (0.40) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL25566025 | 0.77 | HCRTR1 (0.35) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL31432518 | 0.77 | KAT6A (0.38) | KAT6AKAT7KAT6B | |
| SCHEMBL25564465 | 0.77 | KAT6A (0.38) | KAT6AKAT7KAT6B | |
| SCHEMBL21609189 | 0.76 | KAT6A (0.41) | KAT6AKAT7KAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |