Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | KAT7 | O95251 | 2/20 | 0.38 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006437 | 0.79 | SMN1; SMN2 (0.46) | SCN9ASSTR4KEAP1KAT8 | |
| SCHEMBL16006559 | 0.77 | KEAP1 (0.38) | SCN9AKAT7KAT6BKAT6AKEAP1 | |
| SCHEMBL16158008 | 0.76 | SCN9A (0.40) | SCN9AKAT7KAT6BKAT6AKEAP1 | |
| SCHEMBL24249760 | 0.75 | EPHX2 (0.42) | SCN9ASSTR4KAT6AKEAP1 | |
| SCHEMBL25639241 | 0.75 | L3MBTL1 (0.46) | SCN9AKEAP1 | |
| SCHEMBL31605639 | 0.74 | KAT6A (0.53) | KAT7KAT6BKAT6AKAT5KAT8 | |
| SCHEMBL21596868 | 0.74 | KAT6A (0.53) | KAT7KAT6BKAT6AKAT5KAT8 | |
| SCHEMBL29268181 | 0.70 | KMT2A (0.56) | SCN9AKAT6AKAT8 | |
| SCHEMBL30881801 | 0.70 | SSTR4 (0.42) | SSTR4PDK2PDK4PDK1CHRNA7 | |
| SCHEMBL16006540 | 0.70 | CA12 (0.35) | SCN9AKAT7KAT6BKAT6AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |