Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28962682 | 0.90 | TDP1 (0.53) | TDP1AKR1B1OR51E2FFAR3LCK | |
| Propylene Glycol SCHEMBL1003896 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2TP53PAX8 | |
| Propylene Glycol SCHEMBL1004146 | 0.89 | — | — | |
| Propylene Glycol SCHEMBL1002868 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2TP53PAX8 | |
| Propylene Glycol SCHEMBL358822 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2FFAR3LCK | |
| Propylene Glycol SCHEMBL49092 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2FFAR3LCK | |
| Propylene Glycol SCHEMBL8850998 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2FFAR3LCK | |
| Propylene Glycol SCHEMBL36041 | 0.89 | — | — | |
| Propylene Glycol SCHEMBL21828462 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2FFAR3LCK | |
| Propylene Glycol SCHEMBL28241687 | 0.89 | TDP1 (0.67) | TDP1AKR1B1OR51E2FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985502-B2 | Containing formic ester additive; cycling properties, electrical capacity, storage during charging | UBE INDUSTRIES, LTD. (JP) | 2011-07-26 | — | — | US | claimed |
| EP-1729365-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME | UBE INDUSTRIES (JP) | 2010-12-22 | — | — | EP | claimed |
| US-20080241704-A1 | Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same | UBE INDUSTRIES, LTD (JP) | 2008-10-02 | — | — | US | claimed |
| EP-1729365-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | Ube Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | claimed |
| CN-209816015-U | Activated carbon purification window film | 大连爱瑞德纳米科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-7985502-B2 | Containing formic ester additive; cycling properties, electrical capacity, storage during charging | UBE INDUSTRIES, LTD. (JP) | 2011-07-26 | — | — | US | disclosed |
| EP-1729365-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME | UBE INDUSTRIES (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-20080241704-A1 | Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same | UBE INDUSTRIES, LTD (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1729365-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME | Ube Industries, Ltd. (JP) | 2006-12-06 | — | — | EP | disclosed |