Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.71 |
| ▸ | ESR1 | P03372 | 3/20 | 0.71 |
| ▸ | MGAM | O43451 | 2/20 | 0.68 |
| ▸ | FASN | P49327 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337235 | 0.92 | MAOA (0.77) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL31423805 | 0.92 | MAOA (0.77) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL1675981 | 0.90 | MAOA (1.00) | MAOAESR2ESR1MGAMFASN | |
| Xanthone SCHEMBL29025600 | 0.90 | MAOA (1.00) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL30599042 | 0.90 | MAOA (1.00) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL21313809 | 0.86 | TTR (0.71) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL20317212 | 0.86 | MAOA (0.73) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL5308204 | 0.85 | MAPT (0.64) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL21327540 | 0.84 | MAOA (0.66) | MAOAESR2ESR1MGAMFASN | |
| SCHEMBL7417081 | 0.84 | MAOA (0.61) | MAOAESR2ESR1MGAMFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741659-B2 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | OSAKA UNIVERSITY (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8741659-B2 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | OSAKA UNIVERSITY (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8741659-B2 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | OSAKA UNIVERSITY (JP) | 2014-06-03 | — | — | US | disclosed |
| CN-102205076-B | Preparation method of sparganium stoloniferum total phenols with analgesic activity | UNIV NANJING CHINESE MEDICINE | 2013-04-03 | — | — | CN | disclosed |
| US-20120238029-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20120238029-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20120238029-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2012-09-20 | — | — | US | disclosed |
| EP-2482076-A1 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | Osaka University (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110183929-A1 | STANDARDIZED EXTRACT AND FRACTION FROM HANCORNIA SPECIOSA LEAVES AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) | 2011-07-28 | — | — | US | disclosed |
| EP-2175275-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND SUBSTANCE, AND USE THEREOF | Osaka University (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | RBM3, HNRNPA3, HNRNPAB | MAOA 1965/4885ESR2 2573/4885ESR1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.