Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572289 | 0.72 | IKBKB (0.45) | PRKD1PRKD2PRKD3KDM4ECYP3A4 | |
| SCHEMBL30612354 | 0.70 | KDM4E (0.46) | KDM4ECYP3A4HSD17B10HRH4HTR2C | |
| SCHEMBL16613201 | 0.69 | ADRB2 (0.52) | PRKD1PRKD2PRKD3KDM4ECYP3A4 | |
| SCHEMBL30955001 | 0.68 | KDM4E (0.40) | PRKD1PRKD2PRKD3KDM4ECYP3A4 | |
| SCHEMBL10169212 | 0.64 | BTK (0.46) | SYKKDM4EHSD17B10IRAK4MEN1 | |
| SCHEMBL16597825 | 0.64 | BTK (0.48) | CYP3A4HSD17B10IRAK4HTR2APRKCA | |
| SCHEMBL4117671 | 0.64 | ALDH1A1 (0.61) | KDM4EIRAK4ALDH1A1 | |
| SCHEMBL10169216 | 0.63 | BTK (0.47) | SYKKDM4EHSD17B10IRAK4MEN1 | |
| SCHEMBL20998482 | 0.63 | PARP1 (0.50) | KDM4EHSD17B10IRAK4MEN1KMT2A | |
| SCHEMBL3686674 | 0.63 | KDM4E (0.47) | PRKD1PRKD2KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |