Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024849 | 0.76 | SMN1; SMN2 (0.42) | BRD4CYP1A2CYP2C9 | |
| SCHEMBL21614781 | 0.76 | BRD4 (0.35) | BRD4CYP1A2BRD2 | |
| SCHEMBL15395900 | 0.76 | BRD4 (0.38) | BRD4BRD2 | |
| SCHEMBL3131565 | 0.72 | SMN1; SMN2 (0.42) | BRD4CYP1A2CYP2C9 | |
| SCHEMBL12094403 | 0.66 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL21987985 | 0.65 | BRD4 (0.54) | BRD4 | |
| SCHEMBL3142696 | 0.63 | KDM4E (0.34) | BRD4CYP1A2CYP2C9 | |
| SCHEMBL18354798 | 0.58 | CHRM5 (0.33) | — | |
| SCHEMBL723744 | 0.57 | — | — | |
| SCHEMBL20690446 | 0.55 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020008317-A1 | ACYLSUFONAMIDE COMPOUNDS USEFUL AS EP3 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-09 | — | — | WO | disclosed |