Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.54 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1E | P28566 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145564 | 0.72 | BRD4 (0.41) | BRD4HTR2CHTR2AHTR1ADRD2 | |
| SCHEMBL3131565 | 0.69 | SMN1; SMN2 (0.42) | BRD4HTR2AHTR1ADRD2 | |
| SCHEMBL9024849 | 0.69 | SMN1; SMN2 (0.42) | BRD4HTR2AHTR1ADRD2 | |
| SCHEMBL16738107 | 0.68 | BRD4 (0.66) | BRD4HTR2CHTR2AHTR1DHTR1E | |
| SCHEMBL20499686 | 0.67 | EZH2 (0.53) | BRD4 | |
| SCHEMBL21614780 | 0.65 | BRD4 (0.41) | BRD4 | |
| SCHEMBL29738463 | 0.64 | CDC7 (0.43) | CDC7PARP10PARP11PARP1CRBN | |
| SCHEMBL21987941 | 0.63 | CDC7 (0.36) | CDC7HTR2APARP10PARP11PARP1 | |
| SCHEMBL34469201 | 0.63 | BRD4 (0.40) | BRD4HTR2CHTR2AHTR1DHTR1E | |
| SCHEMBL19154250 | 0.62 | LRRK2 (0.39) | BRD4CDC7PARP10PARP11PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424195-B | Fused lactam derivatives | 住友制药株式会社 | 2025-03-25 | — | — | CN | disclosed |
| US-20250084090-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2025-03-13 | — | — | US | disclosed |
| US-12180213-B2 | Substituted pyrazoles showing serotonin 5-HT receptor activity | SUMITOMO PHARMA CO. LTD. (JP) | 2024-12-31 | — | — | US | disclosed |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | Sumitomo Pharma Co., Ltd. (JP) | 2023-01-12 | — | — | US | disclosed |
| US-11466007-B2 | Substituted lactams showing serotonin 5-HT receptor activity | Sumitomo Pharma Co., Ltd. (JP) | 2022-10-11 | — | — | US | disclosed |
| EP-3828182-A1 | FUSED RING LACTAM DERIVATIVES | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-10745401-B2 | Condensed lactam derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20200255432-A1 | CONDENSED LACTAM DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-13 | — | — | US | disclosed |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255432-A1 | CONDENSED LACTAM DERIVATIVE | PSEN1, GRIN1, HDAC1 | BRD4 119/4885CDC7 3245/4885RIPK3 2800/4885 |
| US-20250084090-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | BRD4 2127/4885CDC7 4200/4885RIPK3 2295/4885 |
| US-12180213-B2 | Substituted pyrazoles showing serotonin 5-HT receptor activity | HTR5A, HTR1A, TPH1 | BRD4 1218/4885CDC7 4573/4885RIPK3 1290/4885 |
| US-10745401-B2 | Condensed lactam derivative | PSEN1, GRIN1, HDAC1 | BRD4 119/4885CDC7 3245/4885RIPK3 2800/4885 |
| US-11466007-B2 | Substituted lactams showing serotonin 5-HT receptor activity | HTR1A, HTR5A, TPH1 | BRD4 2127/4885CDC7 4200/4885RIPK3 2295/4885 |
| US-20230008875-A1 | SUBSTITUTED LACTAMS SHOWING SEROTONIN 5-HT RECEPTOR ACTIVITY | HTR1A, HTR5A, TPH1 | BRD4 2127/4885CDC7 4200/4885RIPK3 2295/4885 |
| US-20200172543-A1 | CONDENSED LACTAM DERIVATIVE | PSEN1, GRIN1, HDAC1 | BRD4 119/4885CDC7 3245/4885RIPK3 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.