Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689337 | 0.88 | MEN1 (0.71) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL30951249 | 0.88 | MEN1 (0.71) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL27379241 | 0.87 | ALDH1A1 (0.51) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL17816623 | 0.81 | AKR1C3 (0.57) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL22523683 | 0.81 | AKR1C3 (0.57) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL1712844 | 0.81 | ALDH1A1 (0.52) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL2794401 | 0.81 | ALDH1A1 (0.78) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL29407531 | 0.81 | ALDH1A1 (0.78) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL10034433 | 0.81 | ALDH1A1 (0.78) | MEN1GAAKMT2AKDM4EMAPT | |
| SCHEMBL30556528 | 0.81 | ALDH1A1 (0.78) | MEN1GAAKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
| WO-2020007770-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MAOB, TYR, INMT | MEN1 2585/4885GAA 277/4885KMT2A 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.