Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15137702 | 0.96 | ALOX5 (0.51) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL20317137 | 0.93 | ALOX5 (0.50) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL15213984 | 0.92 | ALOX5 (0.51) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL15137701 | 0.89 | PARP14 (0.47) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL23690157 | 0.88 | KDM4E (0.46) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL15138713 | 0.88 | KDM4E (0.46) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL30746697 | 0.88 | KDM4E (0.46) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL15773283 | 0.87 | ALOX5 (0.55) | PARP14ALOX5TDP1MAP3K8ALDH1A1 | |
| SCHEMBL22136358 | 0.87 | ALOX5 (0.53) | PARP14ALOX5KDM4EMEN1GLA | |
| SCHEMBL15681384 | 0.86 | ALOX5 (0.47) | PARP14ALOX5KDM4EMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
| EP-3322693-B1 | A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2020-02-12 | — | — | EP | disclosed |
| WO-2020007770-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MERCK PATENT GMBH (DE) | 2020-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127251-A1 | PROCESS FOR THE PRODUCTION OF ARYLAMINES | MAOB, TYR, INMT | PARP14 987/4885ALOX5 3383/4885KDM4E 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.