⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483277 | 0.84 | — | — | |
| SCHEMBL57743 | 0.84 | ACE (0.40) | — | |
| SCHEMBL6970651 | 0.81 | — | — | |
| SCHEMBL4202343 | 0.80 | ACE (0.38) | — | |
| SCHEMBL4305395 | 0.79 | — | — | |
| SCHEMBL17228576 | 0.79 | GPR84 (0.41) | — | |
| SCHEMBL7107900 | 0.79 | — | — | |
| SCHEMBL3126483 | 0.79 | — | — | |
| SCHEMBL15743583 | 0.77 | TSHR (0.47) | — | |
| SCHEMBL6568476 | 0.76 | GPR84 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119011-A | Preparation method of high-degradation epoxy resin and insulating material | 合肥工业大学 | 2024-12-13 | — | — | CN | claimed |
| WO-2024001218-A1 | METHOD FOR BIOSYNTHESIS OF 1,4-DIHYDROXY-2-BUTANONE COMPOUND | 中国科学院天津工业生物技术研究所 | 2024-01-04 | — | — | WO | claimed |
| CN-113337546-B | Preparation method of (S) -1,2, 4-butanetriol | 上海启讯医药科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-114524882-B | Method for improving hydrolysis rate of carbohydrate polymer in solution containing cupric salt | 中国科学院大连化学物理研究所 | 2023-03-14 | — | — | CN | claimed |
| CN-115572744-A | Biosynthesis method of 1, 4-dihydroxy-2-butanone compound | 中国科学院天津工业生物技术研究所 | 2023-01-06 | — | — | CN | claimed |
| CN-115109770-A | Benzaldehyde lyase mutant and application thereof in preparation of 1, 4-dihydroxy-2-butanone | 中国科学院天津工业生物技术研究所 | 2022-09-27 | — | — | CN | claimed |
| CN-114524882-A | Method for improving hydrolysis rate of carbohydrate polymer in solution containing cupric salt | 中国科学院大连化学物理研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-112941114-B | Method for synthesizing (S) -1,2, 4-butanetriol by enzyme method | 江苏惠利生物科技有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-113337546-A | Preparation method of (S) -1,2, 4-butanetriol | 上海启讯医药科技有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-112941114-A | Method for synthesizing (S) -1,2, 4-butanetriol by enzyme method | 江苏惠利生物科技有限公司 | 2021-06-11 | — | — | CN | claimed |
| US-20060189545-A1 | Novel chemical entities and methods for their use in treatment of metabolic disorders | ACCERA, INC. | 2006-08-24 | — | — | US | claimed |
| EP-1605950-A2 | NOVEL CHEMICAL ENTITIES AND METHODS FOR THEIR USE IN TREATMENT OF METABOLIC DISORDERS | Accera, Inc. (US) | 2005-12-21 | — | — | EP | claimed |
| WO-2005110429-A1 | PHARMACEUTICAL COMPOSITIONS FOR METABOLIC INSUFFICIENCES | BLASS JOHN P (US) | 2005-11-24 | — | — | WO | claimed |
| US-20050245612-A1 | Pharmaceutical compositions for metabolic insufficiencies | BLASS JOHN P | 2005-11-03 | — | — | US | claimed |
| WO-2004077938-A2 | NOVEL CHEMICAL ENTITIES AND METHODS FOR THEIR USE IN TREATMENT OF METABOLIC DISORDERS | ACCERA INC. (US) | 2004-09-16 | — | — | WO | claimed |
| EP-1032403-A4 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | BLASS JOHN P (US) | 2004-03-31 | — | — | EP | claimed |
| EP-1032403-A1 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999021565-A1 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-05-06 | — | — | WO | claimed |
| US-4240792-A | After-treatment of dyed or printed synthetic fibers | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | claimed |
| US-3976817-A | Method of preparing diffusion transfer image-receiving materials | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-24 | — | — | US | claimed |