Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532617 | 0.93 | LIPC (0.40) | LIPCLIPGP2RY14PTGER4PTGER2 | |
| SCHEMBL23632088 | 0.91 | P2RY14 (0.38) | LIPGP2RY14PTGER4KDM2BCCR2 | |
| SCHEMBL21616645 | 0.91 | P2RY14 (0.38) | LIPGP2RY14PTGER4KDM2BCCR2 | |
| SCHEMBL28626815 | 0.91 | P2RY14 (0.38) | LIPGP2RY14PTGER4KDM2BCCR2 | |
| SCHEMBL28614536 | 0.91 | P2RY14 (0.38) | LIPGP2RY14PTGER4KDM2BCCR2 | |
| SCHEMBL21616597 | 0.90 | SRD5A2 (0.37) | P2RY14PTGER4CCR2KCNH2SRD5A2 | |
| SCHEMBL21616595 | 0.87 | SRD5A2 (0.38) | LIPGP2RY14PTGER4KDM2BCCR2 | |
| SCHEMBL28910599 | 0.87 | P2RY14 (0.37) | P2RY14PTGER4KDM2BSRD5A2LTA4H | |
| SCHEMBL23631928 | 0.86 | P2RY14 (0.37) | P2RY14PTGER4KDM2BCCR2KCNH2 | |
| SCHEMBL23632375 | 0.86 | P2RY14 (0.37) | P2RY14PTGER4KDM2BCCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |