Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 5/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626815 | 1.00 | P2RY14 (0.38) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL23632088 | 1.00 | P2RY14 (0.38) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL21616645 | 1.00 | P2RY14 (0.38) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL21616633 | 0.91 | LIPC (0.40) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL28526814 | 0.91 | SRD5A2 (0.39) | P2RY14SRD5A2PTGER4LIPG | |
| SCHEMBL21616595 | 0.90 | SRD5A2 (0.38) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL21616597 | 0.89 | SRD5A2 (0.37) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL21616632 | 0.88 | P2RY14 (0.37) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL23631928 | 0.88 | P2RY14 (0.37) | P2RY14SRD5A2CCR2KCNH2PTGER4 | |
| SCHEMBL23632375 | 0.88 | P2RY14 (0.37) | P2RY14SRD5A2CCR2KCNH2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072542-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |