SCHEMBL21616786

SCHEMBL21616786

C(Cc1ccncc1)=c1ccc(=CCc2ccncc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP2D6 P10635 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.44
HRH1 P35367 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
CYP11B1 P15538 2/20 0.34
CYP17A1 P05093 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP11B2 P19099 1/20 0.34
HRH3 Q9Y5N1 2/20 0.33
HRH4 Q9H3N8 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FDPS P14324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28301709 0.85 CYP3A4 (0.40) CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL5495225 0.76 CYP3A4 (0.55) CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL28539147 0.75 CYP1A2 (0.43) CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL272745 0.74
SCHEMBL6609419 0.74
SCHEMBL11549923 0.72
SCHEMBL154558 0.72
SCHEMBL1024496 0.72
Bromide SCHEMBL9249645 0.72 CYP3A4 (0.50) CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6
SCHEMBL401609 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820929-A1 COORDINATION POLYMER OF A PRECURSOR CONTAINING CU(I) IONS Centre National de la Recherche Scientifique (FR) 2021-05-19 EP disclosed
WO-2020011557-A1 COORDINATION POLYMER OF A PRECURSOR CONTAINING CU(I) IONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-01-16 WO disclosed