SCHEMBL28539147

SCHEMBL28539147

Cc1c(C)c(=CCc2ccncc2)c(C)c(C)c1=CCc1ccncc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
HSD17B10 Q99714 1/20 0.43
LOXL2 Q9Y4K0 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
NR2F2 P24468 1/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ADRA2C P18825 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
NPC1 O15118 2/20 0.33
KMT2A Q03164 2/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21616786 0.75 CYP3A4 (0.48) CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C9
SCHEMBL1024496 0.72
SCHEMBL18662495 0.71 ALDH1A1 (0.40) CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C9
SCHEMBL5495225 0.71 CYP3A4 (0.55) CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C9
SCHEMBL272745 0.69
SCHEMBL6609419 0.69
SCHEMBL27577717 0.68 CYP3A4 (0.46) CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C9
SCHEMBL151828 0.68 LOXL2 (0.48) CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C9
SCHEMBL42462 0.68
SCHEMBL401609 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108276583-B Cobalt coordination polymer nano material and preparation method and application thereof 淮北师范大学 2021-02-26 CN claimed
CN-108276583-B Cobalt coordination polymer nano material and preparation method and application thereof 淮北师范大学 2021-02-26 CN disclosed