⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9249645 | 0.97 | CYP3A4 (0.50) | — | |
| SCHEMBL31236792 | 0.85 | MAPT (0.50) | — | |
| SCHEMBL6870747 | 0.85 | MAPT (0.50) | — | |
| Phenylacetaldehyde SCHEMBL27881691 | 0.80 | MAOB (0.48) | — | |
| SCHEMBL2636311 | 0.80 | KDM4E (0.53) | — | |
| SCHEMBL5495225 | 0.80 | CYP3A4 (0.55) | — | |
| SCHEMBL9245177 | 0.79 | NAMPT (0.45) | — | |
| SCHEMBL6364651 | 0.78 | MAOB (0.40) | — | |
| SCHEMBL6609419 | 0.78 | — | — | |
| SCHEMBL347894 | 0.77 | LOXL2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | claimed |
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023036707-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-16 | — | — | WO | claimed |
| CN-102741269-A | Gadd45beta targeting agents | IMP INNOVATIONS LTD | 2012-10-17 | — | — | CN | claimed |
| JP-61069760-A | — | — | None | — | — | JP | disclosed |
| WO-2025233901-A1 | ACTIVATORS OF PYRUVATE KINASE ISOFORM M2 AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | BIOHAVEN THERAPEUTICS LTD. (VG) | 2025-11-13 | — | — | WO | disclosed |
| EP-4569560-A1 | AMPHIPHILIC COMPLEXING AGENTS FOR IMPROVED MEMBRANE COMPATIBILITY AND STABILITY OF REDOX SPECIES | Wisconsin Alumni Research Foundation (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024229221-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | CAPULUS THERAPEUTICS, LLC (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | disclosed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-0361300-A1 | Use of 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as drugs, 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as well as processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4681944-A | Process for preparing certain 1-lower alkanoyl or benzoyl-4-(lower alkanoyl or benzoyl-methylidene)-1,4-dihydropyridines or acid addition salts thereof | BRITISH NUCLEAR GROUP SELLAFIELD LIMITED (GB) | 1987-07-21 | — | — | US | disclosed |
| US-4681944-A | Process for preparing certain 1-lower alkanoyl or benzoyl-4-(lower alkanoyl or benzoyl-methylidene)-1,4-dihydropyridines or acid addition salts thereof | BRITISH NUCLEAR GROUP SELLAFIELD LIMITED (GB) | 1987-07-21 | — | — | US | disclosed |
| JP-S6169760-A | (4-PYRIDYL)ALKANEDIONE COMPOUND AND ITS PREPARATION | KOEI CHEM CO LTD | 1986-04-10 | — | — | JP | disclosed |
| EP-0029665-B1 | ANTIBACTERIAL DERIVATIVES OF MONIC ACID, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4312874-A | PYRAN KETONES | BEECHAM GROUP LIMITED (GB) | 1982-01-26 | — | — | US | disclosed |
| EP-0029665-A1 | Antibacterial derivatives of monic acid, processes for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1981-06-03 | — | — | EP | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |