SCHEMBL21617226

SCHEMBL21617226

CCOP(=O)(OCC)Oc1cccc(Nc2ccc(OCc3ccccn3)cc2C2CC2)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 4/20 0.39
▸ CCNT1 O60563 3/20 0.39
▸ CDK9 P50750 3/20 0.39
▸ RHOA P61586 1/20 0.37
▸ DGAT1 O75907 1/20 0.37
▸ PTK6 Q13882 1/20 0.36
▸ GPR132 Q9UNW8 1/20 0.36
▸ MCHR1 Q99705 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPK14 Q16539 3/20 0.35
▸ SMO Q99835 3/20 0.35
▸ TYK2 P29597 1/20 0.35
▸ JAK3 P52333 1/20 0.35
▸ EGFR P00533 1/20 0.35
▸ ERBB2 P04626 1/20 0.35
▸ ERBB4 Q15303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21623448 0.88 DGAT1 (0.40) CNR2RHOADGAT1PTK6GPR132
SCHEMBL31504377 0.87 CNR2 (0.39) CNR2MCHR1MAPK14SMO
SCHEMBL21617171 0.87 CNR2 (0.39) CNR2MCHR1MAPK14SMO
SCHEMBL21617241 0.86 DGAT1 (0.40) CNR2CCNT1CDK9RHOADGAT1
SCHEMBL23272832 0.84 TYK2 (0.39) CNR2RHOADGAT1GPR132MCHR1
SCHEMBL31504427 0.84 TYK2 (0.39) CNR2RHOADGAT1GPR132MCHR1
SCHEMBL23307998 0.82 EGFR (0.39) CNR2RHOADGAT1MCHR1LMNA
SCHEMBL33372527 0.81 DGAT1 (0.39) CNR2RHOADGAT1GPR132MCHR1
SCHEMBL21617195 0.80 MET (0.44) CNR2RHOADGAT1PTK6MCHR1
SCHEMBL21623513 0.80 EGFR (0.43) CNR2RHOADGAT1PTK6MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820850-B1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-04-01 — — EP disclosed
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 — — US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R CNR2 496/4885CCNT1 2413/4885CDK9 3866/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R CNR2 496/4885CCNT1 2413/4885CDK9 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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