SCHEMBL21617237

SCHEMBL21617237

O=C(NCCC1CCC1)c1cccc(Nc2ccc(OCc3ccccn3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GPR132 Q9UNW8 1/20 0.44
▸ MAPK14 Q16539 3/20 0.44
▸ SMO Q99835 3/20 0.44
▸ CHRM4 P08173 6/20 0.43
▸ PARP10 Q53GL7 1/20 0.43
▸ MEN1 O00255 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31504406 1.00 GPR132 (0.44) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL31504383 0.98 GPR132 (0.44) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL21617201 0.98 GPR132 (0.44) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL21617285 0.97 HPGD (0.45) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL31504443 0.97 HPGD (0.45) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL21617274 0.96 GPR132 (0.45) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL31504336 0.96 GPR132 (0.45) GPR132MAPK14SMOCHRM4PARP10
SCHEMBL21617242 0.89 MEN1 (0.47) GPR132MAPK14SMOPARP10MEN1
SCHEMBL31504392 0.89 MEN1 (0.47) GPR132MAPK14SMOPARP10MEN1
SCHEMBL21617302 0.89 SMO (0.44) GPR132MAPK14SMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820850-B1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-04-01 — — EP disclosed
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 — — US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 — — US disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R GPR132 2767/4885MAPK14 3219/4885SMO 978/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R GPR132 2767/4885MAPK14 3219/4885SMO 978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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