Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.46 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619861 | 1.00 | RORC (0.46) | RORCWDR91TRPA1 | |
| SCHEMBL21619846 | 0.95 | RORC (0.49) | RORCWDR91 | |
| SCHEMBL21620254 | 0.89 | RORC (0.48) | RORC | |
| SCHEMBL21620089 | 0.88 | PPARD (0.46) | RORCWDR91 | |
| SCHEMBL28588632 | 0.87 | ACACB (0.47) | RORC | |
| SCHEMBL28588631 | 0.87 | ACACB (0.47) | RORC | |
| SCHEMBL21619709 | 0.87 | RORC (0.46) | RORCWDR91TRPA1 | |
| SCHEMBL21619864 | 0.86 | RORC (0.47) | RORC | |
| SCHEMBL21619532 | 0.85 | RORC (0.47) | RORCTRPA1 | |
| SCHEMBL21620156 | 0.84 | RORC (0.51) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |