Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619978 | 0.90 | RORC (0.41) | RORC | |
| SCHEMBL21619846 | 0.88 | RORC (0.49) | RORC | |
| SCHEMBL21619861 | 0.86 | RORC (0.46) | RORC | |
| SCHEMBL21619504 | 0.86 | RORC (0.46) | RORC | |
| SCHEMBL21619532 | 0.85 | RORC (0.47) | RORC | |
| SCHEMBL21620065 | 0.85 | RORC (0.46) | RORC | |
| SCHEMBL21619709 | 0.84 | RORC (0.46) | RORC | |
| SCHEMBL21619484 | 0.84 | RORC (0.48) | RORC | |
| SCHEMBL21619717 | 0.83 | RORC (0.52) | RORC | |
| SCHEMBL21619610 | 0.83 | RORC (0.52) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |