Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619519 | 0.95 | RORC (0.55) | RORCTRPA1CA1CA2CA7 | |
| SCHEMBL21619482 | 0.95 | RORC (0.55) | RORCTRPA1CA1CA2CA7 | |
| SCHEMBL28532892 | 0.90 | RORC (0.51) | RORC | |
| SCHEMBL21619763 | 0.89 | ALDH1A1 (0.53) | RORC | |
| SCHEMBL21620020 | 0.89 | RORC (0.55) | RORC | |
| SCHEMBL21620030 | 0.89 | RORC (0.55) | RORC | |
| SCHEMBL21619676 | 0.88 | RORC (0.52) | RORC | |
| SCHEMBL21620027 | 0.88 | RORC (0.52) | RORCTRPA1 | |
| SCHEMBL21620018 | 0.87 | RORC (0.54) | RORC | |
| SCHEMBL21620096 | 0.87 | EPHX2 (0.43) | RORCTRPA1EPHX2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |