Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.78 |
| ▸ | FNTB | P49356 | 7/20 | 0.78 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162264 | 0.97 | FNTA (0.77) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL14722419 | 0.95 | FNTA (0.80) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL4736266 | 0.90 | FNTA (0.78) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL1311793 | 0.89 | FNTA (0.81) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL14721324 | 0.89 | FNTA (0.64) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL2162860 | 0.89 | FNTA (0.80) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL2162288 | 0.89 | FNTA (0.74) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL2161763 | 0.88 | FNTA (1.00) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL17817386 | 0.88 | FNTA (1.00) | FNTAFNTBSRD5A1SRD5A2NPC1L1 | |
| SCHEMBL1310374 | 0.88 | FNTA (0.85) | FNTAFNTBSRD5A1SRD5A2NPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160339041-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2016-11-24 | — | — | US | claimed |
| US-20150056269-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2015-02-26 | — | — | US | claimed |
| EP-2747750-A2 | LIPOSOME COMPRISING AT LEAST A CHOLESTEROL DERIVATIVE | Trophos (FR) | 2014-07-02 | — | — | EP | claimed |
| WO-2013026989-A2 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2013-02-28 | — | — | WO | claimed |
| US-20160339041-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2016-11-24 | — | — | US | disclosed |
| EP-1991235-B1 | USE OF 3,5-SECO-4-NORCHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE MEDICAMENT | TROPHOS (FR) | 2016-11-02 | — | — | EP | disclosed |
| US-9045393-B2 | Derivatives of 3.5-seco-4-norcholestane and use thereof | TROPHOS (FR) | 2015-06-02 | — | — | US | disclosed |
| US-20150056269-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2015-02-26 | — | — | US | disclosed |
| EP-2747750-A2 | LIPOSOME COMPRISING AT LEAST A CHOLESTEROL DERIVATIVE | Trophos (FR) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026989-A2 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | TROPHOS (FR) | 2013-02-28 | — | — | WO | disclosed |
| EP-1786759-B1 | NOVEL DERIVATIVES OF 3,5-SECO-4-NORCHOLESTANE AND USE THEREOF | TROPHOS (FR) | 2012-07-04 | — | — | EP | disclosed |
| US-7985774-B2 | Use of 3,5-seco-4-nor-cholestane derivatives for obtaining a cytoprotective drug | TROPHOS (FR) | 2011-07-26 | — | — | US | disclosed |
| US-20090312434-A1 | USE OF 3,5-SECO-4-NOR-CHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE DRUG | TROPHOS (FR) | 2009-12-17 | — | — | US | disclosed |
| EP-1991235-A1 | USE OF 3,5-SECO-4-NORCHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE MEDICAMENT | Trophos (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20080275130-A1 | Novel Derivatives of 3.5-Seco-4-Norcholestane and Use Thereof | TROPHOS (FR) | 2008-11-06 | — | — | US | disclosed |
| WO-2008056059-A2 | 4-AZASTEROL DERIVATIVES, METHODS FOR THE SYNTHESIS THEREOF AND USE OF SAME AS DRUGS | TROPHOS (FR) | 2008-05-15 | — | — | WO | disclosed |
| WO-2007101925-A1 | USE OF 3,5-SECO-4-NORCHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE MEDICAMENT | TROPHOS (FR) | 2007-09-13 | — | — | WO | disclosed |
| EP-1786759-A1 | NOVEL DERIVATIVES OF 3,5-SECO-4-NORCHOLESTANE AND USE THEREOF | Trophos (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006027454-A1 | NOVEL DERIVATIVES OF 3,5-SECO-4-NORCHOLESTANE AND USE THEREOF | TROPHOS (FR) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160339041-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | LIPA, NPC1L1, CETP | FNTA 120/4885FNTB 906/4885SRD5A1 1025/4885 |
| US-20080275130-A1 | Novel Derivatives of 3.5-Seco-4-Norcholestane and Use Thereof | HSD3B1, HSD3B2, CYP11B1 | FNTA 1004/4885FNTB 1178/4885SRD5A1 10/4885 |
| US-20090312434-A1 | USE OF 3,5-SECO-4-NOR-CHOLESTANE DERIVATIVES FOR OBTAINING A CYTOPROTECTIVE DRUG | NR1H4, CYP27A1, NPC1 | FNTA 574/4885FNTB 635/4885SRD5A1 126/4885 |
| US-20150056269-A1 | LIPOSOME COMPRISING AT LEAST ONE CHOLESTEROL DERIVATIVE | LIPA, NPC1L1, CETP | FNTA 120/4885FNTB 906/4885SRD5A1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.