Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619740 | 0.89 | SMN1; SMN2 (0.46) | RORCKCNH2CA1CA2CA7 | |
| SCHEMBL21619935 | 0.87 | RORC (0.47) | RORCKCNH2LDHALDHBCA1 | |
| SCHEMBL21620055 | 0.86 | RORC (0.46) | RORCKCNH2LDHALDHBRORA | |
| SCHEMBL21619864 | 0.85 | RORC (0.47) | RORC | |
| SCHEMBL21620059 | 0.84 | RORC (0.59) | RORCCA1CA2CA7 | |
| SCHEMBL21619710 | 0.84 | RORC (0.59) | RORCCA1CA2CA7 | |
| SCHEMBL21619978 | 0.82 | RORC (0.41) | RORCCA1CA2CA7 | |
| SCHEMBL21619610 | 0.78 | RORC (0.52) | RORCCA1CA2CA7EPHX2 | |
| SCHEMBL21619717 | 0.78 | RORC (0.52) | RORCCA1CA2CA7EPHX2 | |
| SCHEMBL28537438 | 0.78 | NR1H2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |