Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619828 | 0.94 | ACACB (0.47) | KMT2AACACBMEN1CYP1A2CYP2C9 | |
| SCHEMBL21619965 | 0.81 | NOTUM (0.46) | PROKR1PRCP | |
| SCHEMBL21616639 | 0.81 | KDM4E (0.48) | ACACBMAP4K4CYP2C9CYP2C19AVPR1A | |
| SCHEMBL21619819 | 0.79 | ACACB (0.46) | ACACBPROKR1AVPR1ACYP3A4 | |
| SCHEMBL21620073 | 0.78 | KDM4E (0.46) | ACACBCYP2C9CYP2C19KDM4EABL1 | |
| SCHEMBL30474477 | 0.76 | MAPT (0.55) | KMT2AACACBMEN1CYP1A2CYP2C9 | |
| SCHEMBL28537487 | 0.76 | MAPT (0.55) | KMT2AACACBMEN1CYP1A2CYP2C9 | |
| SCHEMBL21619788 | 0.76 | NOTUM (0.51) | AVPR1ACYP3A4 | |
| SCHEMBL14671602 | 0.75 | KMT2A (0.54) | KMT2AMAP4K4MEN1KDM4EABL1 | |
| SCHEMBL13115713 | 0.74 | ADRA1A (0.53) | MAP4K4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |