Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474477 | 1.00 | MAPT (0.55) | MAPTALDH1A1LMNAMAPK1NPSR1 | |
| SCHEMBL28539978 | 0.86 | ACACB (0.41) | MAPTALDH1A1LMNAMAPK1NPSR1 | |
| SCHEMBL28532606 | 0.82 | NOTUM (0.49) | MAPTALDH1A1LMNAMAPK1POLB | |
| SCHEMBL21619828 | 0.81 | ACACB (0.47) | ALDH1A1LMNAL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL2514843 | 0.81 | MAPT (0.56) | MAPTALDH1A1LMNAMAPK1NPSR1 | |
| SCHEMBL21616639 | 0.80 | KDM4E (0.48) | LMNACYP2C9KDM4EABL1ACACB | |
| SCHEMBL21620073 | 0.80 | KDM4E (0.46) | LMNACYP2C9KDM4EABL1ACACB | |
| SCHEMBL28532287 | 0.79 | CHRNB2 (0.53) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28537453 | 0.79 | MAPT (0.45) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL30474474 | 0.79 | MAPT (0.45) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |