Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312347 | 0.81 | TSHR (0.47) | HDAC6MCHR1CYP11B1CYP11B2 | |
| SCHEMBL29760167 | 0.78 | ALOX15 (0.37) | HDAC6MCHR1 | |
| SCHEMBL24577742 | 0.78 | KDM4E (0.36) | HDAC6MCHR1 | |
| SCHEMBL27284833 | 0.78 | KDM4E (0.36) | HDAC6MCHR1 | |
| SCHEMBL24820166 | 0.77 | — | — | |
| SCHEMBL27281817 | 0.77 | CYP2D6 (0.43) | — | |
| SCHEMBL26750989 | 0.77 | MCHR1 (0.31) | MCHR1 | |
| SCHEMBL27282238 | 0.77 | CYP2D6 (0.43) | — | |
| SCHEMBL30148840 | 0.75 | HSD17B10 (0.46) | HDAC6MCHR1 | |
| SCHEMBL21666874 | 0.74 | MCHR1 (0.31) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |