Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620073 | 0.86 | KDM4E (0.46) | ACACBAOC3SCN10ACYP3A4SLC6A9 | |
| SCHEMBL21619819 | 0.85 | ACACB (0.46) | ACACBAOC3SCN10ACYP3A4SLC6A9 | |
| SCHEMBL21616612 | 0.84 | CYP3A4 (0.43) | ACACBAOC3SCN10ACYP3A4SLC6A9 | |
| SCHEMBL28539978 | 0.81 | ACACB (0.41) | ACACBAOC3SCN10ACYP3A4SLC6A9 | |
| SCHEMBL23636875 | 0.80 | LIPG (0.49) | ACACB | |
| SCHEMBL17832257 | 0.77 | SCN9A (0.44) | MCHR1GRM2 | |
| SCHEMBL17832258 | 0.77 | DHFR (0.48) | CYP3A4 | |
| SCHEMBL21619936 | 0.74 | ACACB (0.38) | ACACBPROKR1HTR2C | |
| SCHEMBL17832213 | 0.74 | OGA (0.43) | AOC3 | |
| SCHEMBL21620016 | 0.74 | TRIM24 (0.48) | PROKR1HTR2CNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |