Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 17/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621133 | 0.78 | ATF4 (0.48) | ATF4 | |
| SCHEMBL19569233 | 0.78 | ATF4 (0.62) | ATF4 | |
| SCHEMBL21621148 | 0.77 | ATF4 (0.47) | ATF4ALDH1A1 | |
| SCHEMBL30026091 | 0.77 | ATF4 (0.76) | ATF4 | |
| SCHEMBL19569675 | 0.77 | ATF4 (0.76) | ATF4 | |
| SCHEMBL21621077 | 0.77 | NPC1 (0.48) | ATF4ALDH1A1 | |
| SCHEMBL21621065 | 0.76 | ATF4 (0.45) | ATF4 | |
| SCHEMBL19555359 | 0.75 | ATF4 (0.64) | ATF4 | |
| SCHEMBL19569583 | 0.75 | ATF4 (0.64) | ATF4 | |
| SCHEMBL19569507 | 0.74 | ATF4 (0.79) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020012339-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-01-16 | — | — | WO | disclosed |