Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 15/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621068 | 0.93 | HDAC4 (0.44) | ATF4HDAC4ALDH1A1GAAMEN1 | |
| SCHEMBL21621065 | 0.93 | ATF4 (0.45) | ATF4MEN1MAPTKMT2A | |
| SCHEMBL21621077 | 0.90 | NPC1 (0.48) | ATF4ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL21621133 | 0.89 | ATF4 (0.48) | ATF4MEN1KMT2A | |
| SCHEMBL23773229 | 0.87 | ATF4 (0.54) | ATF4HDAC4 | |
| SCHEMBL23773253 | 0.83 | ATF4 (0.56) | ATF4HDAC4MEN1MAPTMAPK1 | |
| SCHEMBL23773390 | 0.83 | ATF4 (0.58) | ATF4 | |
| SCHEMBL23773235 | 0.80 | ATF4 (0.55) | ATF4 | |
| SCHEMBL21621143 | 0.80 | ATF4 (0.53) | ATF4 | |
| SCHEMBL23773097 | 0.79 | ATF4 (0.49) | ATF4HDAC4MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020012339-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-01-16 | — | — | WO | disclosed |