SCHEMBL2162276

SCHEMBL2162276

CC(=O)Oc1cc2ccc(O)cc2oc1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
MIF P14174 7/20 0.63
MEN1 O00255 6/20 0.63
KMT2A Q03164 6/20 0.63
KDM4E B2RXH2 1/20 0.63
S1PR4 O95977 1/20 0.63
GLA P06280 1/20 0.63
GAA P10253 1/20 0.63
MAPT P10636 1/20 0.63
S1PR1 P21453 1/20 0.63
HSD17B3 P37058 1/20 0.59
POLB P06746 1/20 0.57
PFKFB3 Q16875 1/20 0.55
PKM P14618 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
HTT P42858 1/20 0.53
ESR2 Q92731 1/20 0.53
GAPDH P04406 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764982 0.88 POLB (0.57) CA9CA12MIFMEN1KMT2A
SCHEMBL250387 0.84 MIF (0.68) CA9CA12MIFMEN1KMT2A
SCHEMBL27527189 0.84 POLB (0.53) CA9MIFMEN1KMT2AKDM4E
SCHEMBL17092888 0.83 CA12 (0.64) CA9CA12MIFMEN1KMT2A
SCHEMBL18141852 0.81 POLB (0.59) CA9CA12MIFMEN1KMT2A
SCHEMBL1045399 0.81 KDM4E (0.61) CA9CA12MIFMEN1KMT2A
SCHEMBL250038 0.80 MIF (0.60) CA9MIFMEN1KMT2AKDM4E
SCHEMBL31280892 0.80 MIF (0.60) CA9MIFMEN1KMT2AKDM4E
Methyl Alcohol SCHEMBL27953712 0.79 KDM4E (0.59) CA9CA12MIFMEN1KMT2A
SCHEMBL6264767 0.79 CA9 (1.00) CA9CA12MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985417-B2 Method of lipid structure preparation YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2011-07-26 US disclosed
EP-1809246-B1 METHOD OF INSERTION OF A LIPID-LINKED MOIETY INTO A PRE-FORMED LIPID ASSEMBLY USING MICROWAVES ALZA CORP (US) 2008-07-16 EP disclosed
EP-1809246-A1 METHOD OF INSERION OF A LIPID-LINKED MOIETY INTO A PRE-FORMED LIPID ASSEMBLY USING MICROWAVES ALZA CORPORATION (US) 2007-07-25 EP disclosed
US-20060121105-A1 Method of lipid structure preparation YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-06-08 US disclosed
WO-2006042270-A1 METHOD OF INSERION OF A LIPID-LINKED MOIETY INTO A PRE-FORMED LIPID ASSEMBLY USING MICROWAVES ALZA CORPORATION (US) 2006-04-20 WO disclosed