SCHEMBL8764982

SCHEMBL8764982

O=C(O)Oc1cc2ccc(O)cc2oc1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
HSD17B3 P37058 1/20 0.55
MIF P14174 8/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
KDM4E B2RXH2 3/20 0.55
GLA P06280 3/20 0.55
GAA P10253 3/20 0.55
S1PR4 O95977 2/20 0.55
MAPT P10636 2/20 0.55
S1PR1 P21453 2/20 0.55
NPC1 O15118 2/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
ESR2 Q92731 1/20 0.53
CA9 Q16790 3/20 0.51
PTGS1 P23219 1/20 0.51
PFKFB3 Q16875 1/20 0.51
FLT3 P36888 1/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2162276 0.88 CA9 (0.65) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL27527189 0.84 POLB (0.53) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL18141852 0.81 POLB (0.59) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL6036799 0.81 MAOB (0.58) POLBMEN1KMT2AKDM4ENPC1
SCHEMBL250387 0.81 MIF (0.68) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL9175246 0.77 KDM4E (0.68) MEN1KMT2AKDM4EGLAGAA
SCHEMBL8640209 0.77 POLB (0.47) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL250038 0.77 MIF (0.60) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL31280892 0.77 MIF (0.60) POLBHSD17B3MIFMEN1KMT2A
SCHEMBL37883 0.76 MAOA (0.76) HSD17B3MIFMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-2718458-B1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2015-07-08 EP claimed
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP claimed
EP-0362339-B1 Use of a support with immobilized molecules or substances thereon SLEYTR UWE B (AT) 1995-05-31 EP disclosed
EP-0362339-A1 PROCESS FOR IMMOBILIZING OR DEPOSITING MOLECULES OR SUBSTANCES ON A SUPPORT. SLEYTR UWE B (AT) 1990-04-11 EP disclosed
EP-0247993-B1 METHOD OF PREPARING CARRIER MATERIALS FOR OPTICAL SENSORS AVL AG (CH) 1989-12-20 EP disclosed
WO-1989009406-A1 PROCESS FOR IMMOBILIZING OR DEPOSITING MOLECULES OR SUBSTANCES ON A SUPPORT SLEYTR UWE B (AT) 1989-10-05 WO disclosed
EP-0247993-A1 Method of preparing carrier materials for optical sensors AVL AG (CH) 1987-12-02 EP disclosed