Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553275 | 0.90 | PARP14 (0.54) | ALOX5PARP14PRKDCMAPTPIK3CD | |
| SCHEMBL21125713 | 0.89 | ALOX5 (0.43) | ALOX5PARP14PRKDCMAPTLIMK1 | |
| SCHEMBL30152022 | 0.85 | LIMK1 (0.46) | ALOX5PARP14MAPTF9LIMK1 | |
| SCHEMBL29876020 | 0.85 | LIMK1 (0.46) | ALOX5PARP14MAPTF9LIMK1 | |
| SCHEMBL283191 | 0.85 | LIMK1 (0.46) | ALOX5PARP14MAPTF9LIMK1 | |
| SCHEMBL12996531 | 0.85 | ALOX5 (0.71) | ALOX5PARP14PRKDCMAPTPIK3CD | |
| SCHEMBL24457 | 0.85 | MAPT (0.48) | ALOX5PARP14MAPTGPR3HCRTR1 | |
| SCHEMBL29400549 | 0.85 | MAPT (0.48) | ALOX5PARP14MAPTGPR3HCRTR1 | |
| SCHEMBL17827359 | 0.83 | ALOX5 (0.69) | ALOX5PARP14PRKDCMAPTPIK3CD | |
| SCHEMBL1687975 | 0.83 | ALOX5 (0.69) | ALOX5PARP14PRKDCMAPTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820965-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |
| WO-2020011658-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-01-16 | — | — | WO | disclosed |