SCHEMBL30152022

SCHEMBL30152022

OB(O)c1cccc2c1sc1c(-c3ccccc3)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.46
ALOX5 P09917 1/20 0.41
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
MAPT P10636 1/20 0.36
MCL1 Q07820 1/20 0.36
PARP14 Q460N5 1/20 0.35
F9 P00740 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MGLL Q99685 2/20 0.34
CYP17A1 P05093 1/20 0.34
CYP1A2 P05177 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
FGFR1 P11362 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29876020 1.00 LIMK1 (0.46) LIMK1ALOX5PDCD1CD274MAPT
SCHEMBL283191 1.00 LIMK1 (0.46) LIMK1ALOX5PDCD1CD274MAPT
SCHEMBL17416280 0.97 LIMK1 (0.43) LIMK1ALOX5PDCD1CD274MAPT
SCHEMBL21125713 0.91 ALOX5 (0.43) LIMK1ALOX5MAPTPARP14MGLL
SCHEMBL21622597 0.86 MGLL (0.37) LIMK1ALOX5PDCD1CD274MAPT
SCHEMBL23623782 0.86 LIMK1 (0.41) LIMK1ALOX5PDCD1CD274MAPT
SCHEMBL21622827 0.85 ALOX5 (0.58) LIMK1ALOX5MAPTPARP14F9
SCHEMBL21125627 0.85 TSHR (0.39) LIMK1ALOX5MAPTALDH1A1HPGD
SCHEMBL14101424 0.84 LIMK1 (0.57) LIMK1ALOX5PDCD1CD274MCL1
SCHEMBL29307812 0.83 MGLL (0.55) LIMK1ALOX5PDCD1CD274MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4410074-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2025-05-21 EP disclosed
EP-4438693-A2 HETEROCYCLIC SPIRO COMPOUNDS Merck Patent GmbH (DE) 2024-10-02 EP disclosed
EP-3708634-B1 HETEROCYCLIC SPIRO COMPOUNDS MERCK PATENT GMBH (DE) 2024-08-14 EP disclosed
EP-3820965-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-01-25 EP disclosed