Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 5/20 | 0.41 |
| ▸ | GABRD | O14764 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20277467 | 0.91 | MAPT (0.50) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL25989887 | 0.90 | GPR3 (0.38) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL2802294 | 0.89 | MAPT (0.52) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL21431979 | 0.88 | TNKS (0.42) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20706688 | 0.88 | MAPT (0.47) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20706801 | 0.88 | MAPT (0.47) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20277487 | 0.88 | MAPT (0.47) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL15836095 | 0.88 | MAPT (0.47) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20462459 | 0.87 | MAPT (0.41) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20821662 | 0.86 | PLA2G2A (0.50) | NPC1MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820965-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |
| WO-2020011658-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-01-16 | — | — | WO | disclosed |