Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.47 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | CCR8 | P51685 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015251 | 0.83 | LPL (0.41) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL21841087 | 0.82 | CCR1 (0.53) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL22963781 | 0.81 | LPL (0.40) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL31577388 | 0.81 | LPL (0.40) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL20587479 | 0.80 | CCR1 (0.40) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL6126262 | 0.80 | LPL (0.53) | LPLLIPGIRAK4PRMT5WDR77 | |
| SCHEMBL18943899 | 0.80 | LPL (0.41) | LPLLIPGCCR1CCR8CCR5 | |
| SCHEMBL29502750 | 0.80 | ALDH1A1 (0.49) | LPLLIPGKDM4EMAPTTP53 | |
| SCHEMBL418496 | 0.80 | ALDH1A1 (0.49) | LPLLIPGKDM4EMAPTTP53 | |
| SCHEMBL31513479 | 0.80 | ALDH1A1 (0.49) | LPLLIPGKDM4EMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820965-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |
| WO-2020011658-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-01-16 | — | — | WO | disclosed |