Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617310 | 0.89 | GABRA1 (0.37) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL31504414 | 0.89 | GABRA1 (0.37) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL31504317 | 0.88 | GABRA1 (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL21617308 | 0.88 | GABRA1 (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL21623436 | 0.87 | RHOA (0.36) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL31504356 | 0.87 | PLAT (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL21617240 | 0.87 | PLAT (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL21623406 | 0.86 | GABRA1 (0.36) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL23272976 | 0.85 | GABRG2 (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 | |
| SCHEMBL31504410 | 0.85 | GABRG2 (0.38) | TYK2JAK3GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122732-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2021-04-29 | — | — | US | disclosed |
| WO-2020011816-A1 | PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | ABIVAX (FR) | 2020-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122732-A1 | ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION | NSUN3, CBR3, C1R | TYK2 2212/4885JAK3 933/4885GABRG2 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.