Rebamipide

Rebamipide

SCHEMBL21623658

O=C(N[C@@H](Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
UBASH3B Q8TF42 1/20 1.00
PPARG P37231 1/20 0.55
ITGB2 P05107 6/20 0.55
ICAM1 P05362 6/20 0.55
ITGAL P20701 6/20 0.55
F11 P03951 2/20 0.54
ERAP2 Q6P179 1/20 0.54
TACR1 P25103 2/20 0.52
CCKBR P32239 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CA2 P00918 1/20 0.48
PIN1 Q13526 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rebamipide SCHEMBL29560992 1.00 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL23346201 1.00 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL221527 1.00 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL5794018 1.00 UBASH3B (1.00) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL9114879 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL28798513 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL27819911 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL2292009 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL26607917 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL
Rebamipide SCHEMBL27858766 0.99 UBASH3B (0.98) UBASH3BPPARGITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020014726-A1 TREATMENT FOR LIVER REGENERATION XENEXUS PHARMACEUTICALS PTY. LTD. (AU) 2020-01-23 WO disclosed